PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer

Recurrence of metastatic breast cancer stemming from acquired endocrine and chemotherapy resistance remains a health burden for women with luminal (ER+) breast cancer. Disseminated ER+ tumor cells can remain viable but quiescent for years to decades. Contributing factors to metastatic spread include...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Truong, Thu H., Benner, Elizabeth A., Hagen, Kyla M., Temiz, Nuri A., Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Trousdell, Marygrace C., Pengo, Thomas, Guillen, Katrin P., Welm, Bryan E., Dos Santos, Camila O., Telang, Sucheta, Lange, Carol A., Ostrander, Julie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238912/
https://ncbi.nlm.nih.gov/pubmed/34103681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01871-w
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