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Triple Negative Breast Cancer is Dependent on the Lysosomal Cholesterol Transporter NPC1

Background: Triple Negative Breast Cancer (TNBC) is an aggressive subtype of breast cancer (BC) with peak rate of metastasis within the first few years post diagnosis and few targeted therapies. Normal epithelial cells and estrogen receptor alpha (ER) positive BC express the microRNA-200c (miR-200c)...

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Détails bibliographiques
Publié dans:J Endocr Soc
Auteur principal: O’Neill, Kathleen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089138/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.2116
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