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Binding pathway determines norepinephrine selectivity for the human β(1)AR over β(2)AR

Beta adrenergic receptors (βARs) mediate physiologic responses to the catecholamines epinephrine and norepinephrine released by the sympathetic nervous system. While the hormone epinephrine binds β(1)AR and β(2)AR with similar affinity, the smaller neurotransmitter norepinephrine is approximately te...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Res
Egile Nagusiak: Xu, Xinyu, Kaindl, Jonas, Clark, Mary J., Hübner, Harald, Hirata, Kunio, Sunahara, Roger K., Gmeiner, Peter, Kobilka, Brian K., Liu, Xiangyu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Singapore 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089101/
https://ncbi.nlm.nih.gov/pubmed/33093660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-00424-2
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