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Dysregulation of the centrosome induced by BRCA1 deficiency contributes to tissue‐specific carcinogenesis
Alterations in breast cancer gene 1 (BRCA1), a tumor suppressor gene, increase the risk of breast and ovarian cancers. BRCA1 forms a heterodimer with BRCA1‐associated RING domain protein 1 (BARD1) and functions in multiple cellular processes, including DNA repair and centrosome regulation. BRCA1 act...
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| Publicado en: | Cancer Sci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8088922/ https://ncbi.nlm.nih.gov/pubmed/33606355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14859 |
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