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Ketamine Induces Lasting Antidepressant Effects by Modulating the NMDAR/CaMKII-Mediated Synaptic Plasticity of the Hippocampal Dentate Gyrus in Depressive Stroke Model
BACKGROUND: Ketamine has been shown to possess lasting antidepressant properties. However, studies of the mechanisms involved in its effects on poststroke depression are nonexistent. METHODS: To investigate these mechanisms, Sprague-Dawley rats were treated with a single local dose of ketamine after...
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| Publicat a: | Neural Plast |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8088363/ https://ncbi.nlm.nih.gov/pubmed/33981335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6635084 |
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