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MR-Clust: clustering of genetic variants in Mendelian randomization with similar causal estimates
MOTIVATION: Mendelian randomization is an epidemiological technique that uses genetic variants as instrumental variables to estimate the causal effect of a risk factor on an outcome. We consider a scenario in which causal estimates based on each variant in turn differ more strongly than expected by...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8088327/ https://ncbi.nlm.nih.gov/pubmed/32915962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa778 |
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