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Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates

Mendelian randomization uses genetic variants to make causal inferences about a modifiable exposure. Subject to a genetic variant satisfying the instrumental variable assumptions, an association between the variant and outcome implies a causal effect of the exposure on the outcome. Complications ari...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Eur J Epidemiol
Main Authors: Burgess, Stephen, Labrecque, Jeremy A.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153517/
https://ncbi.nlm.nih.gov/pubmed/30039250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10654-018-0424-6
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