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Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer

BACKGROUND: Breast cancer (BC) is one of the most common female malignancies in the world. Chemotherapeutic resistance is the major cause of BC therapy failure, leading to tumor recurrence and metastasis. Studies have illustrated the close relationship between glycolysis and BC progression and drug...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Med
Hauptverfasser: Lu, Chao, Qiao, Pengyun, Sun, Yonghong, Ren, Chune, Yu, Zhenhai
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087946/
https://ncbi.nlm.nih.gov/pubmed/33931981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.400
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