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Fructose-1, 6-bisphosphatase 1 interacts with NF-κB p65 to regulate breast tumorigenesis via PIM2 induced phosphorylation

Rationale: Fructose-1, 6-bisphosphatase 1 (FBP1), a rate-limiting enzyme in gluconeogenesis, was recently shown to be a tumor suppressor and could mediate the activities of multiple transcriptional factors via its non-canonical functions. However, the underlying mechanism of posttranscriptional modi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Lu, Chao, Ren, Chune, Yang, Tingting, Sun, Yonghong, Qiao, Pengyun, Han, Xue, Yu, Zhenhai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392005/
https://ncbi.nlm.nih.gov/pubmed/32754266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46861
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