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Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer

BACKGROUND: Breast cancer (BC) is one of the most common female malignancies in the world. Chemotherapeutic resistance is the major cause of BC therapy failure, leading to tumor recurrence and metastasis. Studies have illustrated the close relationship between glycolysis and BC progression and drug...

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Publicado en:Clin Transl Med
Autores principales: Lu, Chao, Qiao, Pengyun, Sun, Yonghong, Ren, Chune, Yu, Zhenhai
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087946/
https://ncbi.nlm.nih.gov/pubmed/33931981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.400
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