Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer

BACKGROUND: Therapeutic resistance is the main cause of death in metastatic colorectal cancer. To investigate genomic plasticity, most specifically of metastatic lesions, associated with response to first‐line systemic therapy, we collected longitudinal liver metastatic samples and characterized the...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Gambaro, Karen, Marques, Maud, McNamara, Suzan, Couetoux du Tertre, Mathilde, Diaz, Zuanel, Hoffert, Cyrla, Srivastava, Archana, Hébert, Steven, Samson, Benoit, Lespérance, Bernard, Ko, Yoo‐Joung, Dalfen, Richard, St‐Hilaire, Eve, Sideris, Lucas, Couture, Felix, Burkes, Ronald, Harb, Mohammed, Camlioglu, Errol, Gologan, Adrian, Pelsser, Vincent, Constantin, André, Greenwood, Celia M.T., Tejpar, Sabine, Kavan, Petr, Kleinman, Claudia L., Batist, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087915/
https://ncbi.nlm.nih.gov/pubmed/33931971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.401
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