Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer

BACKGROUND: Therapeutic resistance is the main cause of death in metastatic colorectal cancer. To investigate genomic plasticity, most specifically of metastatic lesions, associated with response to first‐line systemic therapy, we collected longitudinal liver metastatic samples and characterized the...

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Published in:Clin Transl Med
Main Authors: Gambaro, Karen, Marques, Maud, McNamara, Suzan, Couetoux du Tertre, Mathilde, Diaz, Zuanel, Hoffert, Cyrla, Srivastava, Archana, Hébert, Steven, Samson, Benoit, Lespérance, Bernard, Ko, Yoo‐Joung, Dalfen, Richard, St‐Hilaire, Eve, Sideris, Lucas, Couture, Felix, Burkes, Ronald, Harb, Mohammed, Camlioglu, Errol, Gologan, Adrian, Pelsser, Vincent, Constantin, André, Greenwood, Celia M.T., Tejpar, Sabine, Kavan, Petr, Kleinman, Claudia L., Batist, Gerald
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087915/
https://ncbi.nlm.nih.gov/pubmed/33931971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.401
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