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Sulfated glycans engage the Ang/Tie pathway to regulate vascular development
The angiopoietin (Ang)/Tie pathway is essential for the proper maturation and remodeling of the vasculature. Despite its importance in disease, the mechanisms that control signal transduction through this pathway are poorly understood. Here, we demonstrate that heparan sulfate glycosaminoglycans (HS...
Shranjeno v:
| izdano v: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087285/ https://ncbi.nlm.nih.gov/pubmed/33020664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00657-7 |
| Oznake: |
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