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Melanoma-specific Expression of the Tumor Suppressor Proteins p16 and PTEN is a Favorable Prognostic Factor in Established Melanoma Brain Metastases

OBJECTIVE: PTEN and p16 frequently undergo (epi)genetic aberrations in melanoma resulting in decreased, or absent, protein levels. We investigated the prognostic significance of these tumor suppressor genes in melanoma brain metastases (MBMs). METHODS: Immunohistochemical analysis was performed on a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Melanoma Res
मुख्य लेखकों: Trembath, Dimitri G., Ivanova, Anastasia, Krauze, Michal T., Kirkwood, John M., Nikolaishvilli-Feinberg, Nana, Moschos, Stergios J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086752/
https://ncbi.nlm.nih.gov/pubmed/33871399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000731
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