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Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis
Recent identification of an RNA-binding protein (HuR) that regulates mRNA turnover and translation of numerous transcripts via binding to an ARE in their 3′-UTR involved in inflammation and is abnormally elevated in varied kidney diseases offers a novel target for the treatment of renal inflammation...
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| Publicado no: | Clin Sci (Lond) |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8086301/ https://ncbi.nlm.nih.gov/pubmed/32478392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20200193 |
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