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Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy

The RNA binding protein Human antigen R (HuR) interacts with specific AU-rich domains in target mRNAs and is highly expressed in many cell types, including cardiomyocytes. However, the role of HuR in cardiac physiology is largely unknown. Our results show that HuR undergoes cytoplasmic translocation...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Slone, Samuel, Anthony, Sarah R., Wu, Xiaoqing, Benoit, Joshua B., Aube, Jeffrey, Xu, Liang, Tranter, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032653/
https://ncbi.nlm.nih.gov/pubmed/27521603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.08.005
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