Conformational flexibility and structural variability of SARS-CoV2 S protein

Spike (S) glycoprotein of SARS-CoV2 exists chiefly in two conformations, open and closed. Most previous structural studies on S protein have been conducted at pH 8.0, but knowledge of the conformational propensities under both physiological and endosomal pH conditions is important to inform vaccine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Structure
Hauptverfasser: Pramanick, Ishika, Sengupta, Nayanika, Mishra, Suman, Pandey, Suman, Girish, Nidhi, Das, Alakta, Dutta, Somnath
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2021
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086150/
https://ncbi.nlm.nih.gov/pubmed/33932324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2021.04.006
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