Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or frozen state prior to use. This is a major impediment to deployment in resource-poor settings. Furthermore, several of them use viral vectors or mRNA. In contrast to protein subunit vaccines, there is lim...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Malladi, Sameer Kumar, Singh, Randhir, Pandey, Suman, Gayathri, Savitha, Kanjo, Kawkab, Ahmed, Shahbaz, Khan, Mohammad Suhail, Kalita, Parismita, Girish, Nidhi, Upadhyaya, Aditya, Reddy, Poorvi, Pramanick, Ishika, Bhasin, Munmun, Mani, Shailendra, Bhattacharyya, Sankar, Joseph, Jeswin, Thankamani, Karthika, Raj, V. Stalin, Dutta, Somnath, Singh, Ramandeep, Nadig, Gautham, Varadarajan, Raghavan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832000/
https://ncbi.nlm.nih.gov/pubmed/33154165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016284
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