VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis

The prokaryotic ubiquitous Toxin-antitoxin (TA) modules encodes for a stable toxin and an unstable antitoxin. VapBC subfamily is the most abundant Type II TA system in M. tuberculosis genome. However, the exact physiological role for most of these Type II TA systems are still unknown. Here, we have...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Sharma, Arun, Chattopadhyay, Gopinath, Chopra, Pankaj, Bhasin, Munmun, Thakur, Chandrani, Agarwal, Sakshi, Ahmed, Shahbaz, Chandra, Nagasuma, Varadarajan, Raghavan, Singh, Ramandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517352/
https://ncbi.nlm.nih.gov/pubmed/33042034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02037
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