VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis

The prokaryotic ubiquitous Toxin-antitoxin (TA) modules encodes for a stable toxin and an unstable antitoxin. VapBC subfamily is the most abundant Type II TA system in M. tuberculosis genome. However, the exact physiological role for most of these Type II TA systems are still unknown. Here, we have...

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Vydáno v:Front Microbiol
Hlavní autoři: Sharma, Arun, Chattopadhyay, Gopinath, Chopra, Pankaj, Bhasin, Munmun, Thakur, Chandrani, Agarwal, Sakshi, Ahmed, Shahbaz, Chandra, Nagasuma, Varadarajan, Raghavan, Singh, Ramandeep
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517352/
https://ncbi.nlm.nih.gov/pubmed/33042034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02037
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