Clinically relevant enantiomer specific R‐ and S‐praziquantel pharmacokinetic drug‐drug interactions with efavirenz and ritonavir

We conducted a clinical study to determine the effect of efavirenz and ritonavir on the pharmacokinetics of R‐ and S‐PZQ in healthy male participants. This was toward evaluating the risk of drug‐drug interactions, which may occur after PZQ administration to HIV patients on efavirenz or ritonavir con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacol Res Perspect
Prif Awduron: Mutiti, Chenai Sheilla, Kapungu, Nyasha Nicole, Kanji, Comfort Ropafadzo, Stadler, Nadina, Stingl, Julia, Nhachi, Charles, Hakim, James, Masimirembwa, Collen, Thelingwani, Roslyn Stella
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085964/
https://ncbi.nlm.nih.gov/pubmed/33929078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.769
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