Costunolide suppresses melanoma growth via the AKT/mTOR pathway in vitro and in vivo

Melanoma is the most common type of skin cancer and its incidence is rapidly increasing. AKT, and its related signaling pathways, are highly activated in many cancers including lung, colon, and esophageal cancers. Costunolide (CTD) is a sesquiterpene lactone that has been reported to possess neuropr...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Huang, Hai, Yi, Junkoo, Park, Song, Zhang, Haibo, Kim, Eungyung, Park, Sijun, Kwon, Wookbong, Jang, Soyoung, Zhang, Xiujuan, Chen, Hanyong, Choi, Seong-Kyoon, Kim, Sung-hyun, Liu, Kangddong, Dong, Zigang, Lee, Mee-Hyun, Ryoo, Zaeyoung, Kim, Myoung Ok
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085867/
https://ncbi.nlm.nih.gov/pubmed/33948365
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