Costunolide suppresses melanoma growth via the AKT/mTOR pathway in vitro and in vivo

Melanoma is the most common type of skin cancer and its incidence is rapidly increasing. AKT, and its related signaling pathways, are highly activated in many cancers including lung, colon, and esophageal cancers. Costunolide (CTD) is a sesquiterpene lactone that has been reported to possess neuropr...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Huang, Hai, Yi, Junkoo, Park, Song, Zhang, Haibo, Kim, Eungyung, Park, Sijun, Kwon, Wookbong, Jang, Soyoung, Zhang, Xiujuan, Chen, Hanyong, Choi, Seong-Kyoon, Kim, Sung-hyun, Liu, Kangddong, Dong, Zigang, Lee, Mee-Hyun, Ryoo, Zaeyoung, Kim, Myoung Ok
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2021
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085867/
https://ncbi.nlm.nih.gov/pubmed/33948365
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