Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo

BACKGROUND: Colorectal cancer (CRC) is a clinically challenging malignant tumor worldwide. As a natural product and sesquiterpene lactone, Costunolide (CTD) has been reported to possess anticancer activities. However, the regulation mechanism and precise target of this substance remain undiscovered...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Huang, Hai, Park, Song, Zhang, Haibo, Park, Sijun, Kwon, Wookbong, Kim, Enugyung, Zhang, Xiujuan, Jang, Soyoung, Yoon, Duhak, Choi, Seong-Kyoon, Yi, Jun-koo, Kim, Sung-hyun, Dong, Zigang, Lee, Mee-hyun, Ryoo, Zaeyoung, Kim, Myoung Ok
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010944/
https://ncbi.nlm.nih.gov/pubmed/33785035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01895-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados