Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment

Liver fibrosis (LF) is a dangerous clinical condition with no available treatment. Inflammation plays a critical role in LF progression. Glucocorticoid-induced leucine zipper (GILZ, encoded in mice by the Tsc22d3 gene) mimics many of the anti-inflammatory effects of glucocorticoids, but its role in...

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Udgivet i:Cell Death Dis
Main Authors: Flamini, Sara, Sergeev, Philipp, Viana de Barros, Zenobio, Mello, Tommaso, Biagioli, Michele, Paglialunga, Musetta, Fiorucci, Chiara, Prikazchikova, Tatiana, Pagano, Stefano, Gagliardi, Andrea, Riccardi, Carlo, Zatsepin, Timofei, Migliorati, Graziella, Bereshchenko, Oxana, Bruscoli, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085011/
https://ncbi.nlm.nih.gov/pubmed/33927191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03704-w
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