Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice

Glucocorticoids (GC) are widely used as antiinflammatory/immunosuppressive drugs and antitumor agents in several types of lymphoma and leukemia. Therapeutic doses of GC induce growth-suppressive and cytotoxic effects on various leukocytes including B cells. Molecular mechanisms of GC action include...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Bruscoli, Stefano, Biagioli, Michele, Sorcini, Daniele, Frammartino, Tiziana, Cimino, Monica, Sportoletti, Paolo, Mazzon, Emanuela, Bereshchenko, Oxana, Riccardi, Carlo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2015
Pynciau:
Immunobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705834/
https://ncbi.nlm.nih.gov/pubmed/26276664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-631580
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