Glucocorticoid-Induced Leucine Zipper Inhibits Interferon-Gamma Production in B Cells and Suppresses Colitis in Mice

Glucocorticoid-induced leucine zipper (GILZ) is transcriptionally upregulated by glucocorticoids (GCs) and mediates many of the anti-inflammatory effects of GCs. Since B cell activity has been linked to cytokine production and modulation of inflammatory responses, we herein investigated the role of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bruscoli, Stefano, Sorcini, Daniele, Flamini, Sara, Gagliardi, Andrea, Adamo, Francesco, Ronchetti, Simona, Migliorati, Graziella, Bereshchenko, Oxana, Riccardi, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064738/
https://ncbi.nlm.nih.gov/pubmed/30083167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01720
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