Slow viral propagation during initial phase of infection leads to viral persistence in mice

Immune evasion of pathogens can modify the course of infection and impact viral persistence and pathology. Here, using different strains of the lymphocytic choriomeningitis virus (LCMV) model system, we show that slower propagation results in limited type I interferon (IFN-I) production and viral pe...

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Pubblicato in:Commun Biol
Autori principali: Xu, Haifeng C., Wang, Ruifeng, Shinde, Prashant V., Walotka, Lara, Huang, Anfei, Poschmann, Gereon, Huang, Jun, Liu, Wei, Stühler, Kai, Schaal, Heiner, Bergthaler, Andreas, Pandyra, Aleksandra A., Hardt, Cornelia, Lang, Karl S., Lang, Philipp A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084999/
https://ncbi.nlm.nih.gov/pubmed/33927339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02028-x
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