NK cell–intrinsic FcεRIγ limits CD8(+) T-cell expansion and thereby turns an acute into a chronic viral infection

During viral infection, tight regulation of CD8(+) T-cell functions determines the outcome of the disease. Recently, others and we determined that the natural killer (NK) cells kill hyperproliferative CD8(+) T cells in the context of viral infection, but molecules that are involved in shaping the re...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Duhan, Vikas, Hamdan, Thamer A., Xu, Haifeng C., Shinde, Prashant, Bhat, Hilal, Li, Fanghui, Al-Matary, Yahya, Häussinger, Dieter, Bezgovsek, Judith, Friedrich, Sarah-Kim, Hardt, Cornelia, Lang, Philipp A., Lang, Karl S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605677/
https://ncbi.nlm.nih.gov/pubmed/31220194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007797
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