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Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies
The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antibody. The structure illustrates...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8084527/ https://ncbi.nlm.nih.gov/pubmed/33871352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65005 |
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