Wird geladen...

Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antibody. The structure illustrates...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Caillat, Christophe, Guilligay, Delphine, Torralba, Johana, Friedrich, Nikolas, Nieva, Jose L, Trkola, Alexandra, Chipot, Christophe J, Dehez, François L, Weissenhorn, Winfried
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084527/
https://ncbi.nlm.nih.gov/pubmed/33871352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65005
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!