A Fusion Intermediate gp41 Immunogen Elicits Neutralizing Antibodies to HIV-1

The membrane-proximal external region (MPER) of the human immunodeficiency virus, type 1 (HIV-1) envelope glycoprotein subunit gp41 is targeted by potent broadly neutralizing antibodies 2F5, 4E10, and 10E8. These antibodies recognize linear epitopes and have been suggested to target the fusion inter...

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書誌詳細
主要な著者: Lai, Rachel P. J., Hock, Miriam, Radzimanowski, Jens, Tonks, Paul, Hulsik, David Lutje, Effantin, Gregory, Seilly, David J., Dreja, Hanna, Kliche, Alexander, Wagner, Ralf, Barnett, Susan W., Tumba, Nancy, Morris, Lynn, LaBranche, Celia C., Montefiori, David C., Seaman, Michael S., Heeney, Jonathan L., Weissenhorn, Winfried
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
Microbiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208001/
https://ncbi.nlm.nih.gov/pubmed/25160627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.569566
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