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Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells

LINE-1 (L1) retrotransposons are autonomous transposable elements that can affect gene expression and genome integrity. Potential consequences of exogenous viral infections for L1 activity have not been studied to date. Here, we report that hepatitis C virus (HCV) infection causes a significant incr...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Schöbel, Anja, Nguyen-Dinh, Van, Schumann, Gerald G., Herker, Eva
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084336/
https://ncbi.nlm.nih.gov/pubmed/33872335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009496
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