Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension

Understanding the sensory mechanisms innervating the bladder is paramount to developing efficacious treatments for chronic bladder hypersensitivity conditions. The contribution of Mas-gene-related G protein-coupled receptors (Mrgpr) to bladder signaling is currently unknown. Using male and female mi...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Grundy, Luke, Caldwell, Ashlee, Garcia-Caraballo, Sonia, Grundy, David, Spencer, Nick J., Dong, Xinzhong, Castro, Joel, Harrington, Andrea M., Brierley, Stuart M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2021
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084315/
https://ncbi.nlm.nih.gov/pubmed/33727332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0033-21.2021
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