Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension

Understanding the sensory mechanisms innervating the bladder is paramount to developing efficacious treatments for chronic bladder hypersensitivity conditions. The contribution of Mas-gene-related G protein-coupled receptors (Mrgpr) to bladder signaling is currently unknown. Using male and female mi...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Grundy, Luke, Caldwell, Ashlee, Garcia-Caraballo, Sonia, Grundy, David, Spencer, Nick J., Dong, Xinzhong, Castro, Joel, Harrington, Andrea M., Brierley, Stuart M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084315/
https://ncbi.nlm.nih.gov/pubmed/33727332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0033-21.2021
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