Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

Cyclodipeptide synthases (CDPSs) produce a variety of cyclic dipeptide products by utilising two aminoacylated tRNA substrates. We sought to investigate the minimal requirements for substrate usage in this class of enzymes as the relationship between CDPSs and their substrates remains elusive. Here,...

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Détails bibliographiques
Publié dans:RSC Chem Biol
Auteurs principaux: Harding, Christopher J., Sutherland, Emmajay, Hanna, Jane G., Houston, Douglas R., Czekster, Clarissa M.
Format: Artigo
Langue:Inglês
Publié: RSC 2021
Sujets:
Chemistry
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084100/
https://ncbi.nlm.nih.gov/pubmed/33937777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cb00142b
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