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Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

Cyclodipeptide synthases (CDPSs) produce a variety of cyclic dipeptide products by utilising two aminoacylated tRNA substrates. We sought to investigate the minimal requirements for substrate usage in this class of enzymes as the relationship between CDPSs and their substrates remains elusive. Here,...

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Библиографические подробности
Опубликовано в: :RSC Chem Biol
Главные авторы: Harding, Christopher J., Sutherland, Emmajay, Hanna, Jane G., Houston, Douglas R., Czekster, Clarissa M.
Формат: Artigo
Язык:Inglês
Опубликовано: RSC 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084100/
https://ncbi.nlm.nih.gov/pubmed/33937777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cb00142b
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