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Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme

Cyclodipeptide synthases (CDPSs) produce a variety of cyclic dipeptide products by utilising two aminoacylated tRNA substrates. We sought to investigate the minimal requirements for substrate usage in this class of enzymes as the relationship between CDPSs and their substrates remains elusive. Here,...

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Bibliografiske detaljer
Udgivet i:RSC Chem Biol
Main Authors: Harding, Christopher J., Sutherland, Emmajay, Hanna, Jane G., Houston, Douglas R., Czekster, Clarissa M.
Format: Artigo
Sprog:Inglês
Udgivet: RSC 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084100/
https://ncbi.nlm.nih.gov/pubmed/33937777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cb00142b
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