Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma

BACKGROUND: Soft tissue sarcomas are a heterogeneous group of rare malignant tumors. Advanced soft tissue sarcomas have a poor prognosis, and effective systemic therapies have not been established. Tyrosine kinases are increasingly being used as therapeutic targets for a variety of cancers and soft...

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Vydáno v:Clin Orthop Relat Res
Hlavní autoři: Suehara, Yoshiyuki, Kohsaka, Shinji, Hayashi, Takuo, Akaike, Keisuke, Kurisaki-Arakawa, Aiko, Sato, Shingo, Kobayashi, Eisuke, Mizuno, Sho, Ueno, Toshihide, Morii, Takeshi, Okuma, Tomotake, Kurihara, Taisei, Hasegawa, Nobuhiko, Sano, Kei, Sasa, Keita, Okubo, Taketo, Kim, Youngji, Mano, Hiroyuki, Saito, Tsuyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer 2021
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083907/
https://ncbi.nlm.nih.gov/pubmed/33196586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CORR.0000000000001548
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