IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing’s sarcoma

Ewing's sarcoma (ES) is the second-most frequent pediatric bone tumor. Chromosomal translocation t(11;22)(q24:q12) results in the formation of EWS/FLI1 gene fusion, which is detected in approximately 90% of tumors of the Ewing family. Several transcriptome studies have provided lists of genes a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tanabe, Yu, Suehara, Yoshiyuki, Kohsaka, Shinji, Hayashi, Takuo, Akaike, Keisuke, Mukaihara, Kenta, Kurihara, Taisei, Kim, Youngji, Okubo, Taketo, Ishii, Midori, Kazuno, Saiko, Kaneko, Kazuo, Saito, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865680/
https://ncbi.nlm.nih.gov/pubmed/29581854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24467
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