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Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab

Giant cell tumors of bone (GCTB) are locally aggressive osteolytic bone tumors. Recently, some clinical trials have shown that denosumab is a novel and effective therapeutic option for aggressive and recurrent GCTB. This study was performed to investigate the molecular mechanism underlying the thera...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Mukaihara, Kenta, Suehara, Yoshiyuki, Kohsaka, Shinji, Akaike, Keisuke, Tanabe, Yu, Kubota, Daisuke, Ishii, Midori, Fujimura, Tsutomu, Kazuno, Saiko, Okubo, Taketo, Takagi, Tatsuya, Yao, Takashi, Kaneko, Kazuo, Saito, Tsuyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749282/
https://ncbi.nlm.nih.gov/pubmed/26863138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148401
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