Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab

Giant cell tumors of bone (GCTB) are locally aggressive osteolytic bone tumors. Recently, some clinical trials have shown that denosumab is a novel and effective therapeutic option for aggressive and recurrent GCTB. This study was performed to investigate the molecular mechanism underlying the thera...

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Publicado en:PLoS One
Autores principales: Mukaihara, Kenta, Suehara, Yoshiyuki, Kohsaka, Shinji, Akaike, Keisuke, Tanabe, Yu, Kubota, Daisuke, Ishii, Midori, Fujimura, Tsutomu, Kazuno, Saiko, Okubo, Taketo, Takagi, Tatsuya, Yao, Takashi, Kaneko, Kazuo, Saito, Tsuyoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749282/
https://ncbi.nlm.nih.gov/pubmed/26863138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148401
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