Assessment of Predictive Biomarkers of the Response to Pazopanib Based on an Integrative Analysis of High-grade Soft-tissue Sarcomas: Analysis of a Tumor Sample from a Responder and Patients with Other Soft-tissue Sarcomas

BACKGROUND: Soft-tissue sarcomas are a rare group of malignant tumors that usually are treated with surgical excision and radiation therapy, but recently, pazopanib, an oral tyrosine kinase inhibitor, has been used in patients with metastases who do not respond to standard chemotherapy regimens. Bas...

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Udgivet i:Clin Orthop Relat Res
Main Authors: Suehara, Yoshiyuki, Kohsaka, Shinji, Yamaguchi, Shigeo, Hayashi, Takuo, Kurihara, Taisei, Sano, Kei, Sasa, Keita, Akaike, Keisuke, Ueno, Toshihide, Kojima, Shinya, Ikegami, Masachika, Mizuno, Sho, Okubo, Taketo, Kim, Youngji, Kaneko, Kazuo, Saito, Tsuyoshi, Kato, Shunsuke, Mano, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer 2020
Fag:
Selected Proceedings of the 2019 International Society of Limb Salvage Annual Meeting (Guest Editor: John H. Healey, Md)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594915/
https://ncbi.nlm.nih.gov/pubmed/32567826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CORR.0000000000001322
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