Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p

BACKGROUND: Curcumin has anti-inflammatory effects and qualifies as a potential candidate for the treatment of osteoarthritis (OA). However, curcumin has limited bioavailability. Extracellular vesicles (EVs) are released by multiple cell types and act as molecule carrier during intercellular communi...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Herrmann, Marietta, Brochhausen, Christoph, König, Matthias A., Johnstone, Brian, Grässel, Susanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082633/
https://ncbi.nlm.nih.gov/pubmed/33926561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02317-6
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