TRIM21, a New Component of the TRAIL-Induced Endogenous Necrosome Complex

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a well-known apoptosis inducer and a potential anticancer agent. When caspases and inhibitors of apoptosis proteins (IAPs) are inhibited, TRAIL induces necroptosis. Molecular mechanisms of necroptosis rely on kinase activation, and o...

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Publicat a:Front Mol Biosci
Autors principals: Simoes Eugénio, Mélanie, Faurez, Florence, Kara-Ali, Ghania H., Lagarrigue, Mélanie, Uhart, Perrine, Bonnet, Marion C., Gallais, Isabelle, Com, Emmanuelle, Pineau, Charles, Samson, Michel, Le Seyec, Jacques, Dimanche-Boitrel, Marie-Thérèse
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082149/
https://ncbi.nlm.nih.gov/pubmed/33937329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.645134
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