SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease

The epigenetic modifications, such as DNA methylation and histone acetylation, play a critical role in the pathogenesis of Parkinson's disease (PD). However, the relationship between DNA methylation and histone acetylation in PD is not fully understood. Previous studies have shown that patients...

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Bibliografische gegevens
Gepubliceerd in:Front Neurol
Hoofdauteurs: Li, Xuan, Liu, Te, Wu, Ting-Ting, Feng, Ya, Peng, Si-Jia, Yin, Huiyong, Wu, Yun-Cheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Neurology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082066/
https://ncbi.nlm.nih.gov/pubmed/33935952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.652882
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