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Medicinal Chemistry of P2 and Adenosine Receptors: Common Scaffolds Adapted for Multiple Targets

Prof. Geoffrey Burnstock originated the concept of purinergic signaling. He demonstrated the interactions and biological roles of ionotropic P2X and metabotropic P2Y receptors. This review paper traces the historical origins of many currently used antagonists and agonists for P2 receptors, as well a...

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Vydáno v:Biochem Pharmacol
Hlavní autoři: Jacobson, Kenneth A., IJzerman, Adriaan P., Müller, Christa E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081756/
https://ncbi.nlm.nih.gov/pubmed/33130128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.114311
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