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Xanthines as Adenosine Receptor Antagonists

The natural plant alkaloids caffeine and theophylline were the first adenosine receptor (AR) antagonists described in the literature. They exhibit micromolar affinities and are non-selective. A large number of derivatives and analogs have subsequently been synthesized and evaluated as AR antagonists...

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Autores principales: Müller, Christa, Jacobson, Kenneth A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882893/
https://ncbi.nlm.nih.gov/pubmed/20859796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-13443-2_6
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