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Species differences in structure-activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors

A series of 28 adenosine analogs and 17 xanthines has been assessed as inhibitors of binding of N(6)-R-[(3)H]-phenylisopropyladenosine binding to A1 adenosine receptors in membranes from rat, calf, and guinea pig brain. Potencies of N(6)-alkyl- and N(6)-cycloalkyladenosines are similar in the differ...

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Detalhes bibliográficos
Main Authors: Ukena, Dieter, Jacobson, Kenneth A., Padgett, William L., Ayala, Cristina, Shamim, Mah T., Kirk, Kenneth L., Olsson, Ray O., Daly, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469266/
https://ncbi.nlm.nih.gov/pubmed/3803571
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