8-SUBSTITUTED XANTHINES AS ANTAGONISTS AT A(1)- AND A(2)-ADENOSINE RECEPTORS

Two classes of 8-substituted analogs of theophylline (1,3-dialkylxanthines), having 8-cycloalkyl, 8-cycloalkenyl or 8-(para-substituted aryl) groups, were shown to be potent and, in some cases, receptor subtype selective antagonists at A(1)- and A(2)-adenosine receptors. New analogs based on a funct...

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Detalhes bibliográficos
Main Authors: Jacobson, Kenneth A., de la Cruz, Richard, Schulick, Richard, Kiriasis, Leonidas, Padgeti, William, Pfleiderer, Wolfgang, Kirk, Kenneth L., Neumeyerii, John L., Daly, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469272/
https://ncbi.nlm.nih.gov/pubmed/3178879
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