AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

Retinitis pigmentosa (RP) is an inherited retinal disease affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high-acuity vision. Currently, there is no effective treatment...

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Vydáno v:eLife
Hlavní autoři: Xue, Yunlu, Wang, Sean K, Rana, Parimal, West, Emma R, Hong, Christin M, Feng, Helian, Wu, David M, Cepko, Constance L
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081528/
https://ncbi.nlm.nih.gov/pubmed/33847261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66240
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