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Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa

Retinitis pigmentosa (RP) is a disease that initially presents as night blindness due to genetic deficits in the rod photoreceptors of the retina. Rods then die, causing dysfunction and death of cone photoreceptors, the cell type that mediates high acuity and color vision, ultimately leading to blin...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Wang, Sean K., Xue, Yunlu, Rana, Parimal, Hong, Christin M., Cepko, Constance L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525490/
https://ncbi.nlm.nih.gov/pubmed/31036641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901787116
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