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TNFa knockdown in the retina promotes cone survival in a mouse model of autosomal dominant retinitis pigmentosa
Expression of T17M rhodopsin (T17M) in rods activates the Unfolded Protein Response (UPR) and leads to the development of autosomal dominant retinitis pigmentosa (adRP). The rod death occurs in adRP retinas prior to cone photoreceptor death, so the mechanism by which cone photoreceptors die remains...
Gorde:
| Argitaratua izan da: | Biochim Biophys Acta |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056179/ https://ncbi.nlm.nih.gov/pubmed/27750040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.10.008 |
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